OVERVIEW
LL-37 is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, immune, or regenerative pathways.
What is it?
LL-37 is a synthetic form of a human cathelicidin-derived antimicrobial peptide studied in investigational and in vitro research settings. It is a component of the innate immune system and is naturally produced by various cell types, where it participates in first-line defense and immune signaling processes.
In preclinical and laboratory research models, LL-37 has been examined for its role in antimicrobial activity, immune cell signaling, and inflammatory pathway modulation. Beyond direct pathogen interaction, it has also been studied for its involvement in wound-related signaling, angiogenic processes, and epithelial barrier communication, making it a compound of interest in experimental studies focused on host defense and immune response regulation.
MECHANISM OF INTEREST
|
Pathway |
Description |
|
Angiogenesis |
Observed to influence vascular endothelial pathways. |
|
Tissue Repair |
Supports modeling of gastric, tendon, and muscular healing. |
|
Cytoprotection |
Evaluated for protective effects in oxidative environments. |
KEY RESEARCH APPLICATIONS
- Tissue repair and regeneration research
- Inflammation pathway modeling
- Angiogenesis studies
SPECIFICATIONS
|
Attribute |
Detail |
|
Purity |
≥ 98% (HPLC) |
|
Form |
Lyophilized peptide |
|
Appearance |
White to off-white powder |
|
Molecular Weight |
~1419 Da |
|
Container |
Sterile glass vial |
HANDLING & STORAGE
Lyophilized: Store at –20°C, protect from light and moisture.
Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.
RESEARCH USE ONLY
This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.