
Cellular aging
FOXO4-DRI
Cell-penetrating peptide used in cellular senescence and apoptosis signaling research.
$139.99
/ 10mg vial · TDL-FOX04-10MG
Size
Bundle & Save
Subtotal
$139.99
Ships
Same-day · by 2 pm CT
Free
Shipping over $100, contiguous US
Pay
Card · Crypto · ACH
Research profile
FOXO4-DRI is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, or immune pathways.
FOXO4-DRI is a synthetic, cell-penetrating research peptide developed for investigational and in vitro research use, designed to modulate protein-protein interactions involving the transcription factor FOXO4. It has primarily been studied in cellular senescence research as a tool to explore how senescent cells maintain survival signaling under stress.
In preclinical and laboratory models, FOXO4-DRI has been examined for its ability to disrupt FOXO4-associated signaling complexes that are linked to pro-survival pathways in senescent cells, with downstream effects that can influence apoptosis-related signaling under controlled experimental conditions. These characteristics have made it a compound of interest in experimental studies focused on senescence biology, stress-response signaling, and pathways associated with cellular aging mechanisms.
Mechanism of Interest
- FOXO4–p53 Interaction — Studied for disruption of the FOXO4-p53 complex in senescent cell models.
- Senolytic Research — Investigated in preclinical models of senescent cell clearance.
- Nuclear Localization — Examined for influence on p53 nuclear exclusion in vitro.
Key Research Applications
- Cellular senescence research
- p53 pathway modeling
- Age-associated tissue studies
Research Use Only
This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.
All compounds sold by Tidal are intended exclusively for in-vitro and laboratory research. We do not market our products for human or veterinary use. By placing an order, purchasers acknowledge they are qualified researchers and that materials will be used in compliance with applicable institutional and regulatory standards.
- Purity
- ≥ 99% (HPLC)
- Form
- Lyophilized peptide
- Appearance
- White to off-white powder
- Molecular Weight
- ~5046.74 Da
- Container
- Sterile glass vial
- Sequence
- D-retro-inverso peptide derived from FOXO4-p53 interaction motif
- No reading list yet for this compound.
Questions
- What sizes does FOXO4-DRI come in?
- FOXO4-DRI comes in 10mg vials (lyophilized peptide), from $139.99. Ordering 3, 5 or 10 vials takes 3%, 6% or 12% off.
- When does FOXO4-DRI ship?
- Orders placed before 2 pm CT on a business day ship the same day from the US. Shipping is free on orders over $100 to the contiguous US. Shipping policy →
- Is FOXO4-DRI for human use?
- No. FOXO4-DRI is sold strictly for in-vitro and laboratory research. It is not for human or veterinary use.
Adjacent
Researchers also ordered.

Epithalon
from $54.99
Synthetic tetrapeptide studied for telomerase, DNA stability, and circadian pathways.
Sizes · 10mg · 50mg

5-Amino-1-MQ
from $49.99
Small-molecule NNMT inhibitor studied in cellular metabolism and NAD+ salvage pathway models.
Sizes · 10mg · 50mg

SS-31
from $59.99
Synthetic mitochondria-targeted tetrapeptide for cardiolipin and oxidative pathway research.
Sizes · 10mg · 50mg