IGF-1_LR3 is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, or immune pathways.

What is it?

IGF-1 LR3 is a synthetic analog of insulin-like growth factor 1 developed for investigational and in vitro research use. It incorporates structural modifications, including an extended amino acid sequence and reduced binding affinity to IGF-binding proteins, which are intended to prolong molecular activity and stability in experimental settings.

In preclinical and laboratory research models, IGF-1 LR3 has been examined for its interaction with IGF-1 receptor signaling pathways involved in cellular growth, proliferation, and nutrient-related anabolic signaling. These characteristics have made it a compound of interest in experimental studies exploring muscle cell biology, tissue growth signaling, and metabolic adaptation mechanisms.

Mechanism of Interest

• IGF-1 Receptor — Studied for receptor binding and downstream signaling in cell models.
• Reduced IGFBP Affinity — The Long R3 modification is investigated for decreased binding-protein sequestration.
• PI3K/Akt Signaling — Examined in anabolic signaling pathway models in vitro.

Key Research Applications

• Growth factor signaling research
• Cell proliferation and differentiation studies
• Protein synthesis pathway modeling

HANDLING & STORAGE

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

RESEARCH USE ONLY

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.