
Cellular aging
MOTS-c
Mitochondria-derived peptide for metabolic and mitochondrial-nuclear signaling research.
$39.99
/ 10mg vial · TDL-MOTS-C-10MG
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Subtotal
$39.99
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Same-day · by 2 pm CT
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Every vial, fully documented.
Certificate of analysis · Batch JNK-154641Current
Compound
MOTS-c
Batch
JNK-154641
Verify code
V110P
Tested
May 13, 2026
Method
HPLC (Janoshik Analytical)
Purity
99.1%
Mass match
—
Appearance
—
Storage
2–8°C, lyophilized
HPLC trace · 220 nm
Stylized representation derived from the certificate. See the PDF for the original trace.Research profile
MOTS-c is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, or immune pathways.
What is it?
MOTS-c is a mitochondria-derived peptide encoded within the mitochondrial genome and studied in investigational and in vitro research settings for its role in cellular metabolic signaling. Unlike nuclear-encoded peptides, MOTS-c originates from mitochondrial DNA, positioning it as a unique signaling molecule in mitochondrial-to-nuclear communication pathways.
In preclinical and laboratory research models, MOTS-c has been examined for its influence on energy sensing pathways, insulin-related metabolic signaling, and cellular stress adaptation. These characteristics have made it a compound of interest in experimental studies exploring mitochondrial regulation, metabolic flexibility, and adaptive cellular responses to energetic demand.
Mechanism of Interest
- Mitochondrial-Derived Peptide — Studied as a 16-amino-acid peptide encoded within mitochondrial DNA (MT-RNR1).
- AMPK Signaling — Investigated for influence on AMP-activated protein kinase activity in vitro.
- Folate Cycle — Examined for interaction with methionine-folate metabolism in cell models.
Key Research Applications
- Mitochondrial-derived peptide research
- Metabolic regulation studies
- Energy homeostasis modeling
HANDLING & STORAGE
Lyophilized: Store at –20°C, protect from light and moisture.
Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.
RESEARCH USE ONLY
This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.
All compounds sold by Tidal are intended exclusively for in-vitro and laboratory research. We do not market our products for human or veterinary use. By placing an order, purchasers acknowledge they are qualified researchers and that materials will be used in compliance with applicable institutional and regulatory standards.
- Purity
- ≥ 99% (HPLC)
- Form
- Lyophilized peptide
- Appearance
- White to off-white powder
- Molecular Weight
- 2174.50 Da
- Molecular Formula
- C₁₀₁H₁₅₂N₂₈O₂₂S₂
- CAS Number
- 1627580-64-6
- Container
- Sterile glass vial
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- No reading list yet for this compound.
Questions
- What sizes does MOTS-c come in?
- MOTS-c comes in 10mg & 40mg vials (lyophilized peptide), from $39.99. Ordering 3, 5 or 10 vials takes 3%, 6% or 12% off.
- How is MOTS-c tested?
- The current batch (JNK-154641) was tested on May 13, 2026 by HPLC (Janoshik Analytical), measuring 99.1% purity. Its certificate of analysis is published on this page and in the public COA registry. Open the COA registry →
- When does MOTS-c ship?
- Orders placed before 2 pm CT on a business day ship the same day from the US. Shipping is free on orders over $100 to the contiguous US. Shipping policy →
- Is MOTS-c for human use?
- No. MOTS-c is sold strictly for in-vitro and laboratory research. It is not for human or veterinary use.
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