What sizes does PE-22-28 come in?

PE-22-28 comes in 10mg vials (lyophilized peptide), from $45.00. Ordering 3, 5 or 10 vials takes 3%, 6% or 12% off.

When does PE-22-28 ship?

Orders placed before 2 pm CT on a business day ship the same day from the US. Shipping is free on orders over $100 to the contiguous US.

Is PE-22-28 for human use?

No. PE-22-28 is sold strictly for in-vitro and laboratory research. It is not for human or veterinary use.

Neuro

PE-22-28

Name: PE-22-28
Brand: Tidal Peptides
SKU: TDL-PE-22-28-10MG
Price: 45.00 USD
Availability: InStock

Spadin-derived peptide studied in TREK-1 channel and neuroplasticity signaling models.

$45.00

/ 10mg vial · TDL-PE-22-28-10MG

Size

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Subtotal

$45.00

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Same-day · by 2 pm CT
Free
Shipping over $100, contiguous US
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Research profile

PE-22-28 is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, or immune pathways.

What is it?

PE-22-28 is a synthetic peptide fragment corresponding to amino acids 22–28 of pancreatic polypeptide, developed for investigational and in vitro research use. It is studied as a selective signaling fragment rather than a full-length metabolic hormone.

In preclinical and laboratory research models, PE-22-28 has been examined for its interaction with neuroendocrine and hypothalamic signaling pathways involved in appetite regulation and energy balance. Its fragment-specific activity has made it a compound of interest in experimental studies exploring satiety signaling, feeding behavior modulation, and central metabolic communication mechanisms.

Mechanism of Interest

TREK-1 Channel Blockade — Studied for inhibition of the TREK-1 potassium channel in vitro.
Spadin Derivative — Investigated as a shortened analog of the propeptide-derived spadin sequence.
Neurogenesis Models — Examined for effects on hippocampal neurogenesis markers in preclinical research.

Key Research Applications

Ion channel research
Neuroplasticity pathway modeling
Neurogenesis studies

HANDLING & STORAGE

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

RESEARCH USE ONLY

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.

All compounds sold by Tidal are intended exclusively for in-vitro and laboratory research. We do not market our products for human or veterinary use. By placing an order, purchasers acknowledge they are qualified researchers and that materials will be used in compliance with applicable institutional and regulatory standards.

Questions

What sizes does PE-22-28 come in?: PE-22-28 comes in 10mg vials (lyophilized peptide), from $45.00. Ordering 3, 5 or 10 vials takes 3%, 6% or 12% off.
When does PE-22-28 ship?: Orders placed before 2 pm CT on a business day ship the same day from the US. Shipping is free on orders over $100 to the contiguous US. Shipping policy →
Is PE-22-28 for human use?: No. PE-22-28 is sold strictly for in-vitro and laboratory research. It is not for human or veterinary use.

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