PT-141 (Bremelanotide) is a synthetic research peptide utilized in preclinical laboratory models to investigate melanocortin receptor signaling and related neuropeptide pathways.

What is it?

PT-141 is a synthetic melanocortin peptide developed for investigational and in vitro research use. It is structurally derived from alpha-melanocyte-stimulating hormone (α-MSH) and is designed to selectively interact with melanocortin receptor pathways rather than vascular smooth muscle mechanisms.

In preclinical and experimental research settings, PT-141 has been examined for its influence on central nervous system signaling associated with motivation, arousal, and behavioral response pathways. Its receptor-level activity has made it a compound of interest in laboratory models exploring neuroendocrine communication and melanocortin system function.

Mechanism of Interest

• Melanocortin Signaling — Studied for interaction with melanocortin receptor pathways in preclinical models.
• Neuropeptide Signaling — Evaluated in research settings for central neuropeptide signaling mechanisms.
• Receptor Binding — Used in laboratory studies examining receptor–ligand interaction dynamics.

Key Research Applications

• Melanocortin receptor signaling research
• Neuropeptide and CNS pathway modeling
• Receptor binding and signaling studies

Handling & Storage

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

Research Use Only

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.