Sema

OVERVIEW

Sema is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, immune, or regenerative pathways.

What is it? (Sema / GLP-1)

Sema is a synthetic peptide analog modeled after human glucagon-like peptide-1 (GLP-1), developed for investigational and in vitro research use. It is designed to structurally and functionally resemble a naturally occurring incretin hormone involved in metabolic signaling following nutrient intake.

Incretins are a class of gut-derived peptides released in response to food consumption, particularly carbohydrates and fats. In preclinical and laboratory research settings, GLP-1 analogs such as Sema have been studied for their role in glucose-dependent insulin signaling, meaning insulin-related activity is observed primarily when glucose levels are elevated rather than under baseline conditions.

GLP-1 (glucagon-like peptide-1) is the primary incretin pathway associated with Sema in research models.

Within experimental settings, GLP-1–focused signaling has been associated with coordinated effects on insulin secretion modulation, glucagon signaling balance, gastric emptying dynamics, and central satiety-related communication. As a result, Sema has become a compound of interest in laboratory studies exploring metabolic regulation, energy balance, and appetite-related neuroendocrine signaling through GLP-1–specific mechanisms.

MECHANISM OF INTEREST

KEY RESEARCH APPLICATIONS

- Tissue repair and regeneration research

- Inflammation pathway modeling

- Angiogenesis studies

SPECIFICATIONS

HANDLING & STORAGE

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

RESEARCH USE ONLY

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.